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カタログ番号	製品名	別名	ターゲット
TP1497L	Mast Cell Degranulating Peptide HR-2 acetate	Mast Cell Degranulating Peptide HR-2 acetate(80388-04-1 free base)	Others
	Mast Cell Degranulating Peptide HR-2 acetate from giant hornet Vespa orientalis that has biological effects similar to mast cell degranulating peptide from bee venom.		Others
TP1568	Mast cell degranulating peptide (28-49)
	Mast cell degranulating peptide (28-49) is a bee venom depolarizer that can improve the cGMP content of cerebellum tablets in mice.
TP1497	Mast Cell Degranulating Peptide HR-2
	Peptide from giant hornet Vespa orientalis that has biological effects similar to mast cell degranulating peptide from bee venom.
T9689	M4205		c-Kit
	M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, 13, 17.		c-Kit
T6488	Epinastine hydrochloride	Alesion,Epinastine HCl,WAL-801CL HCl,Elestat	5-HT Receptor , Histamine Receptor
	Epinastine hydrochloride (WAL-801CL HCl) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.		5-HT Receptor , Histamine Receptor
T0994	Ketotifen fumarate	HC 20511 fumarate	PDE , Histamine Receptor
	Ketotifen fumarate (HC 20511 fumarate) is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators.		PDE , Histamine Receptor
T15259	Evatanepag	CP-533536 free acid	Prostaglandin Receptor
	Evatanepag (CP-533536 free acid) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.CP-533536 demonstrated the ability to heal fractures when administered l...		Prostaglandin Receptor
T0211	Azelastine	Azelastina,Astelin,Azelastinum	SARS-CoV , Histamine Receptor
			SARS-CoV , Histamine Receptor
T15772	Lodoxamide tromethamine	U-42585E	Histamine Receptor
	Lodoxamide tromethamine is a mast cell stabilizer with anti-allergic properties and can be used in studies about the treatment of asthma and allergic conjunctivitis.		Histamine Receptor
T10811	Chymase-IN-1		Others
	Chymase-IN-1 is a selective, orally active inhibitor of human mast cell chymase (IC50: 29 nM).		Others
T4566	Lodoxamide	Lodoxamidum	GPR , Histamine Receptor
	Lodoxamide (Lodoxamidum) is an antiallergic drug acting as a mast-cell stabilizer. It is effective in the treatment of asthma and allergic conjunctivitis.		GPR , Histamine Receptor
T1170	Olopatadine hydrochloride	Olopatadine HCl,KW4679,ALO4943A	5-HT Receptor , Histamine Receptor
	Olopatadine hydrochloride (ALO4943A) is an antihistamine with mast-cell stabilizing properties used as eye drops in the treatment of ALLERGIC CONJUNCTIVITIS.		5-HT Receptor , Histamine Receptor
T13623	Compound 48/80 trihydrochloride	C48/80 trihydrochloride	Phospholipase
	Compound 48/80 trihydrochloride (C48/80 trihydrochloride) is a mixture of N-methyl-p-methoxyphenethylamine and formaldehyde in a condensation reaction.Compound 48/80 trihydrochloride is a mast cell degranulator and hista...		Phospholipase
T29221	(R)-ZINC-3573	ZINC 3573	Others
	(R)-ZINC-3573 is a potent and highly selective MRGPRX2 probe. (R)-ZINC-3573 activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release.		Others
T25360	Eclazolast	RHC2871,RHC-2871,REV2871,REV 2871,RHC 2871	Others
	Eclazolast (RHC 2871) is a lipophilic anti-allergic compound that inhibits mediator release in a mast cell model.Eclazolast inhibits extracellular secretion by affecting only the direct processes associated with Fc(epsil...		Others
T3979	Emedastine	LY188695,Emadine	Histamine Receptor
	Emedastine (LY188695) is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity. Emedastine reversibly and competitively blocks histamine by binding to H1 receptors, thus blocking its...		Histamine Receptor
T2609	Masitinib	AB1010	Apoptosis , FAK , c-Fms , FGFR , Bcr-Abl , PDGFR , Src , c-Kit , Hck
	Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs. Since its introduction in November 2008 it has been distributed under the commercial name Masivet...
T1139	Salbutamol	Albuterol,AH-3365	Adrenergic Receptor
	Salbutamol (Albuterol) stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3', 5'-adenosine monophosphate (cAMP). Salbutamol ...		Adrenergic Receptor
TP1956L	PKC ζ pseudosubstrate acetate	PKC ζ pseudosubstrate acetate (799764-07-1 free base)	PKC
	PKC ζ pseudosubstrate acetate is an inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide. Consists of amino acids 113 - 129 of PKC ζ pseudosubstrate domain linked by...		PKC
T30587	Brl 22321	Brl22321,Brl-22321
	Brl 22321 is a mast cell stabilizer.
T35319	Zy 15109	N-Acetyl-aspartyl magnesium glutamate,Zy15109,Magnesium N-acetyl-aspartylglutamate
	Zy 15109 can be used as inhaled mast cell stabilizer.
T17001	Tazanolast	Tazalest,TO 188,Tazanol	Others
	Tazanolast is a selective mast-cell-stabilizing drug.		Others
T38326	Cromolyn (sodium salt hydrate)
	Cromolyn is a chromone complex that acts as a mast cell stabilizer, preventing the release of histamine. Its mechanism of action is thought to involve an interference with the antigen-stimulated calcium transport across ...
T30561	Bombolitin V
	Bombolitin V is a mast cell degranulosic peptide from the venom of the bumblebee Megabombus Pennsylvanicus.
T41103	Compound 48/80	Poly-p-methoxyphenethylmethylamine
	Compound 48/80, also known as Poly-p-methoxyphenethylmethylamine, is a commonly utilized mast cell activator in animal and tissue models. This compound exerts its effect by stimulating trimeric G-proteins at the mast cel...
T34796	TEI-9063	TEI9063
	TEI-9063 is a stable and highly specific prostacyclin analogue of prostacyclin receptor in mast cell tumor p-815 cells.
T29969	AMG-126737	105RSZ5CNS,AMG 126737,SCHEMBL7986111
	AMG-126737 is an effective human lung mast cell trypsin inhibitor with potential therapeutic effect in lung diseases.
T40081	APC 366 TFA
	APC 366 (TFA) is a potent irreversible inhibitor of mast cell tryptase. It is particularly useful in studies related to allergic diseases.
T71814	ST026567
	ST026567 is a potent mast cell (MC) activator which promotes de novo synthesis of cytokines and induces the release of eicosanoids from human and mouse MCs.
T68689	2',3'-Dihydroxypuberulin
	2',3'-Dihydroxypuberulin is a natural inhibitor for FcεRI expression on mast cell from Verbasucum thapsus L. 2',3'-Dihydroxypuberulin was isolated from Pterocaulon balansae and P. lanatum.
T70193	APC-366 HCl
	APC-366 is a selective inhibitor of the mast cell tryptase that inhibits tryptase-induced histamine release from human tonsil and lung cells.
TP1408	Peptide 401
	Peptide 401 is an antimicrobial peptide (AMP) derived from the venom of bees and wasps. Peptide 401 induces mast cell degranulation, activating histamine release from peritoneal mast cells. Additionally, peptide 401 exhi...
T71711	ST029248
	ST029248 is a potent mast cell (MC) activator, promoting de novo synthesis of cytokines and inducing the release of eicosanoids from human and mouse MCs.
T76621	Suc-Ala-Ala-Pro-Phe-SBzl
	Suc-Ala-Ala-Pro-Phe-SBzl serves as a substrate for rat intestinal mast cell protease (RMCP I), rat skeletal muscle mast cell protease (RMCP II), and Chymotrypsin. Additionally, it undergoes hydrolysis by glycine (R208G) ...
T21462	Olopatadine	Opatanol,Patanol,KW-4943A,KW-4679
	Olopatadine, an antihistamine, as well as anticholinergic and mast cell stabilizer, is used for the treatment of itching associated with allergic conjunctivitis (eye allergies). There is also a potential for Olopatadine ...
T14829	Bromoenol lactone	(6E)-Bromoenol lactone	Phospholipase
	Bromoenol lactone is a suicide-based irreversible, selective, potent inhibitor of calcium-independent phospholipase A2 (iPLA2β; IC50: ~7 μM). It inhibits antigen-stimulated mast cell exocytosis without blocking Ca2+ infl...		Phospholipase
T63394	MrgprX2 antagonist-6
	MrgprX2 antagonist-6 is a potent antiallergic agent with inhibitory effects on mast cell degranulation.
T63766	MrgprX2 antagonist-7
	MrgprX2 antagonist-7 is an anti-allergic agent with significant anti-allergic effects and inhibits mast cell degranulation.
T81515	Peptide 12d
	Peptide 12d, an antimicrobial peptide derived from wasp venom, induces antimicrobial effects through the stimulation of mast cell degranulation [1].
T76095	Granuliberin R
	Granuliberin R, a dodecapeptide derived from the skin of the frog Rana rugosa, is a novel amphibian-origin mast cell degranulating peptide. It has the ability to target rat peritoneal mast cells, prompting them to releas...
T17099	Timapiprant sodium	OC000459 sodium	Others
	Timapiprant sodium inhibits mast cell activation of Th2 lymphocytes and eosinophils. Timapiprant sodium is a potent and selective D prostanoid receptor 2 antagonist. Timapiprant sodium potently displaces [3H] PGD2 from h...		Others
T73433	MS47134
	MS47134, a selective and potent MRGPRX4 agonist, exhibits an EC50 of 149 nM and holds potential for researching pain, itch, and mast cell-mediated hypersensitivity.
T35669	Neuromedin C (trifluoroacetate salt)
	Neuromedin C is a bombesin-like neuropeptide that stimulates uterine smooth muscle contraction and the release of gastrin , somatostatin, and amylase in rats. Neuromedin C is a truncated form of gastrin-releasing peptide...
T69059	Cromoglicate sodium hydrate
	Cromoglicic acid , cromolyn (USAN), cromoglycate (former BAN), or cromoglicate, is traditionally described as a mast cell stabilizer, and is commonly marketed as the sodium salt sodium cromoglicate or cromolyn sodium. ...
TP1956	PKC ζ pseudosubstrate
	Inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide. Consists of amino acids 113 - 129 of PKC ζ pseudosubstrate domain linked by a disulphide bridge to the Antennap...
T60366	Epinastine
	Epinastine (WAL801), a potent, selective, and orally-active antihistamine and mast cell stabilizer, functions as a histamine H1 receptor antagonist. It also inhibits IL-8 release from human eosinophils, showcasing antial...
T36545	Prostaglandin D2 methyl ester	Prostaglandin D2 methyl ester
	Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis. It causes vasodilation, flushing, hypoten...
T22189	APC 366
	APC 366 is a selective inhibitor of mast cell tryptase with Ki of 7.1 μM. APC 366 inhibits antigen-induced early asthmatic response (EAR), late asthmatic response (LAR), and bronchial hyperresponsiveness (BHR) in a sheep...
TP1910	CALP1
	Cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site; produces CaM-dependent activation of phosphodiesterase. Also binds to cytoplasmic sites on other Ca2+ channels, including NMDA and HIV-...
TP2058	Catestatin
	Non-competitive nicotinic cholinergic antagonist; selectively inhibits nicotinic-stimulated catecholamine secretion from chromaffin cells and noradrenergic neurons (IC50 ~ 200 nM). Blocks nicotinic-induced cationic signa...

Compounds

Mast Cell Degranulating Peptide HR-2 acetate

TP1497L

Synonym: Mast Cell Degranulating Peptide HR-2 acetate(80388-04-1 free base)

Target: Others

Mast cell degranulating peptide (28-49)

TP1568

Synonym:

Target:

Mast Cell Degranulating Peptide HR-2

Epinastine hydrochloride

T6488

Synonym: Alesion,Epinastine HCl,WAL-801CL HCl,Elestat

Target: 5-HT Receptor, Histamine Receptor

Ketotifen fumarate

T0994

Synonym: HC 20511 fumarate

Target: PDE, Histamine Receptor

Evatanepag

T15259

Synonym: CP-533536 free acid

Target: Prostaglandin Receptor

Azelastine

T0211

Synonym: Azelastina,Astelin,Azelastinum

Target: SARS-CoV, Histamine Receptor

Lodoxamide tromethamine

T15772

Synonym: U-42585E

Target: Histamine Receptor

Target: GPR, Histamine Receptor

Olopatadine hydrochloride

T1170

Synonym: Olopatadine HCl,KW4679,ALO4943A

Target: 5-HT Receptor, Histamine Receptor

Compound 48/80 trihydrochloride

T13623

Synonym: C48/80 trihydrochloride

Target: Phospholipase

Synonym: RHC2871,RHC-2871,REV2871,REV 2871,RHC 2871

Target: Others

Emedastine

T3979

Synonym: LY188695,Emadine

Target: Histamine Receptor

Masitinib

T2609

Synonym: AB1010

Target: Apoptosis, FAK, c-Fms, FGFR, Bcr-Abl, PDGFR, Src, c-Kit, Hck

Salbutamol

T1139

Synonym: Albuterol,AH-3365

Target: Adrenergic Receptor

PKC ζ pseudosubstrate acetate

TP1956L

Synonym: PKC ζ pseudosubstrate acetate (799764-07-1 free base)

Target: PKC

Brl 22321

T30587

Synonym: Brl22321,Brl-22321

Target:

Zy 15109

T35319

Synonym: N-Acetyl-aspartyl magnesium glutamate,Zy15109,Magnesium N-acetyl-aspartylglutamate

Target:

Tazanolast

T17001

Synonym: Tazalest,TO 188,Tazanol

Target: Others

Cromolyn (sodium salt hydrate)

Synonym: Poly-p-methoxyphenethylmethylamine

Synonym: 105RSZ5CNS,AMG 126737,SCHEMBL7986111

2',3'-Dihydroxypuberulin

Suc-Ala-Ala-Pro-Phe-SBzl

Synonym: Opatanol,Patanol,KW-4943A,KW-4679

Target:

Bromoenol lactone

T14829

Synonym: (6E)-Bromoenol lactone

Target: Phospholipase

Synonym: OC000459 sodium

Neuromedin C (trifluoroacetate salt)

T35669

Synonym:

Target:

Cromoglicate sodium hydrate

T69059

Synonym:

Target:

PKC ζ pseudosubstrate

Prostaglandin D2 methyl ester

T36545

Synonym: Prostaglandin D2 methyl ester

カタログ番号	製品名	別名	ターゲット
T4946	(+)-Columbianetin acetate	COLUMBIANETIN ACETATE	Others
	(+)-Columbianetin acetate (COLUMBIANETIN ACETATE) may be helpful in regulating mast cell-mediated allergic inflammatory responses.The absorption of (+)-Columbianetin acetate is a passive diffusion process without pH-depe...		Others
TN1516	Cnidicin		NOS , NO Synthase
	Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM). Cnidicin exhibits a significant inhibition on the pr...		NOS , NO Synthase
T6943	Picropodophyllin	AXL1717,Picropodophyllin (PPP),Picropodophyllotoxin,PPP	Apoptosis , IGF-1R
	Picropodophyllin (Picropodophyllin (PPP)) (PPP) is a specific IGF-1R inhibitor (IC50: 1 nM). Picropodophyllin specifically inhibits the activity and downregulates the cellular expression of IGF1R without interfering with...		Apoptosis , IGF-1R
T5S1286	(+)-Columbianetin	(S)-Columbianetin,Columbianetin	Antifungal
	(+)-Columbianetin ((S)-Columbianetin) is a new phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage, it also has antifungal activity. (+)-Columbianetin has anti-inflammatory effect...		Antifungal
T3S0027	Picropodophyllotoxin	AXL 1717,Picropodophyllin	IGF-1R
	Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential anti...		IGF-1R
T5S2343	Acetylshikonin	Acetyl shikonin	Others , P450 , AChE
	1. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC5 of over 2 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and ang...		Others , P450 , AChE
TN2895	3,5-Dicaffeoyl-epi-quinic acid		IL Receptor , p38 MAPK , TNF , Caspase , JNK , Histamine Receptor
	3,5-Dicaffeoyl-epi-quinic acid shows anti-inflammatory activity, it may improve mast cell-mediated inflammatory diseases.
TN5279	Zeorin		ATPase , Calcium Channel , Antifection , Histamine Receptor
	Zeorin shows strong inhibition activity against bacteria and fungi. It markedly exhibits inhibitory activity on histamine release from mast cell induced by DNP24-BSA, it shows potent inhibitory effect by 40% decrease of ...		ATPase , Calcium Channel , Antifection , Histamine Receptor
TN5647	Confluentin
	Confluentin has antimicrobial activity against the gram-positive bacteria.Confluentin significantly inhibits compound 48/80-induced histamine release from rat peritoneal mast cells. Confluentin also shows weak cytotoxici...
TN3325	9-O-Feruloyl-5,5'-dimethoxylariciresinol		IL Receptor , TNF
	(+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol may have anti-allergic inflammatory effect, it can inhibit release of histamine from mast cells. It shows cytotoxicity against a small panel of human tumor cell lines, ...		IL Receptor , TNF
T37272	9(S),12(S),13(S)-TriHOME
	9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble ...

天然物製品

(+)-Columbianetin acetate

T4946

Synonym: COLUMBIANETIN ACETATE

Target: NOS, NO Synthase

Picropodophyllin

T6943

Synonym: AXL1717,Picropodophyllin (PPP),Picropodophyllotoxin,PPP

Target: Apoptosis, IGF-1R

(+)-Columbianetin

T5S1286

Synonym: (S)-Columbianetin,Columbianetin

Target: Antifungal

Picropodophyllotoxin

T3S0027

Synonym: AXL 1717,Picropodophyllin

Target: IGF-1R

Acetylshikonin

T5S2343

Synonym: Acetyl shikonin

Target: Others, P450, AChE

3,5-Dicaffeoyl-epi-quinic acid

TN2895

Synonym:

Target: IL Receptor, p38 MAPK, TNF, Caspase, JNK, Histamine Receptor

Zeorin

TN5279

Synonym:

Target: ATPase, Calcium Channel, Antifection, Histamine Receptor

9-O-Feruloyl-5,5'-dimethoxylariciresinol

TN3325

Synonym:

Target: IL Receptor, TNF

9(S),12(S),13(S)-TriHOME

T37272

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-01470	SCF Protein, Human, Recombinant	Human	E. coli
	Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultu...
TMPJ-00166	SCF Protein, Mouse, Recombinant	Mouse	E. coli
	Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gameto...
TMPJ-00051	IL-3 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPH-02581	Chymase 1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. Chymase 1 Protein, Mouse, Recombinant (His) is expressed i...
TMPY-04139	MCEMP1 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	MCEMP1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 36 kDa and the accession number is A0A384NYE9.
TMPH-02499	Allergin-1 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction. Allergin-1...
TMPY-02574	Chymase 1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	The STR polymorphism in the CMA1 gene is associated with asthma and that this association is even stronger with atopic asthma. CMA1 and IL-4 in atopic asthma and for IL-4 in atopy in general. The local angiotensin II sys...
TMPY-04969	Allergin 1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Allergin 1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.8 kDa and the accession number is Q3TB92-1.
TMPH-00486	Chymase Protein, Canine, Recombinant (His & SUMO)	Canine	E. coli
	Chymase Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli.
TMPJ-00894	SCF Protein, Rat, Recombinant (His)	Rat	E. coli
	Stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesi...
TMPH-01641	CPA3 Protein, Human, Recombinant (His)	Human	E. coli
	CPA3 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPY-04963	Allergin 1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Allergin 1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.8 kDa and the accession number is Q7Z6M3-1.
TMPY-05061	Allergin 1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Allergin 1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.1 kDa and the accession number is Q7Z6M3-1.
TMPY-01027	Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Mast Cell Protease 1 (MMCP-1), also known as MCP-1, MCPT-1 and β-chymase, is a member of the Chymase family of chymotrypsin-like serine proteases. MCPT-1 is a 26 kDa β-chymase that is a component of mast cell granules. I...
TMPJ-00897	TPSB2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Tryptase beta-2(Tpsb2), also known as Mast cell protease 6(mMCP-6), belongs to the peptidase S1 family and Tryptase subfamily. Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled...
TMPJ-00895	SCF Protein, Rat, Recombinant (HEK293, His)	Rat	HEK293 Cells
	SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, ...
TMPJ-00402	CD117 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	C-Kit/SCF R is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to ...
TMPJ-01204	TPSAB1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(T...
TMPJ-01465	GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)	Human	E. coli
	Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of...
TMPJ-00042	TSLP Protein, Human, Recombinant	Human	E. coli
	Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino aci...
TMPY-03968	Secretogranin II Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Kit ligand, also known as Hematopoietic growth factor KL, Mast cell growth factor, Steel factor, Stem cell factor, c-Kit ligand, Kitlg and KITL, is a single-pass type I membrane protein that belongs to the SCF family. KI...
TMPJ-00187	CD300A Protein, Human, Recombinant (hFc & His)	Human	HEK293 Cells
	CD300A is a single-pass type I membrane protein which belongs to the CD300 family. It contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD300 family of myeloid immunoglobulin receptors includes activating (CD30...
TMPH-02258	TPSB2 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. TPSB2 Protein, Human, Recombinant (E....
TMPH-02257	TPSB2 Protein, Human, Recombinant (His & Myc)	Human	P. pastoris (Yeast)
	Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. TPSB2 Protein, Human, Recombinant (Hi...
TMPH-03396	TPSAB1 Protein, Rat, Recombinant (His & Myc & SUMO)	Rat	E. coli
	Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. TPSAB1 Protein, Rat, Recombinant (His...
TMPH-02957	TPSAB1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. TPSAB1 Protein, Mouse, Recombinant (H...
TMPH-00064	MRJP1 Protein, Apis mellifera, Recombinant (His)	Apis mellifera	P. pastoris (Yeast)
	Induces the differentiation of honeybee larvae into queens through an Egfr-mediated signaling pathway. Promotes body size increase by activating p70 S6 kinase, stimulates ovary development by augmenting the titer of vite...
TMPH-03267	CD300f/CD300LF Protein, Rat, Recombinant (His & Myc & SUMO)	Rat	E. coli
	Acts as an inhibitory receptor for myeloid cells and mast cells. Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which...
TMPK-01303	TPSAB1 protein, Cynomolgus, Recombinant (His)	Cynomolgus	E. coli
	TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsinlike activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this...
TMPK-01165	MCEMP1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	A cecal ligation and puncture-induced sepsis mouse model was established to determine the expression of mast cell expression membrane protein 1 (MCEMP1). MCEMP1 in T lymphocytes isolated from sepsis mice were up- or down...
TMPJ-00281	CADM1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Cell adhesion molecule 1(CADM1) is a single-pass type I membrane protein and belongs to the nectin family. It contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. C...
TMPK-00038	TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi)	Human	HEK293 Cells
	Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of ...
TMPK-00482	TSLP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated	Cynomolgus	HEK293 Cells
	Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of ...
TMPK-00037	TSLP Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of ...
TMPK-00040	TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi), Biotinylated	Human	HEK293 Cells
	Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of ...
TMPK-00039	TSLP Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of ...
TMPJ-00898	CD72 Protein, Human, Recombinant (Trx & His)	Human	E. coli
	B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 exists as a disulfide-linked homodimer and contains one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, mon...
TMPJ-00189	TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	T cell immunoglobulin and mucin domain 3 is a member of the TIM family of immune regulating molecules. Mature cynomolgus TIM3 consists of a 182 amino acid (aa)extracellular domain (ECD), a 21 aa transmembrane segment, an...
TMPK-00617	IL-13 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast ce...
TMPJ-01338	TSLP Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Thymic stromal lymphopoietin (TSLP) is a protein belonging to the cytokine family, contains 140 amino acids. It is known to play an important role in the maturation of T cell populations through activation of antigen pre...
TMPJ-01096	SLP-76 Protein, Human, Recombinant (His)	Human	E. coli
	Lymphocyte cytosolic protein 2（LCP2）contains a SAM domain and a SH2 domain. It is highly expressed in spleen, thymus and peripheral blood leukocytes, T-cell and monocytic cell lines, but expressed at lower level in B-cel...
TMPJ-00305	SIRP alpha Protein, Cynomolgus, Recombinant (aa 31-369, His)	Cynomolgus	HEK293 Cells
	Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can expre...
TMPJ-00243	Serpin B6 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Serpin B6 belongs to the serpin family. Serpin B6 localizes to the cytoplasm. Serpin B6 is expressed in many tissues, abundantly by mast cells in different tissues and mastocytoma lesions. Serpin B6 may be involved in th...
TMPJ-00233	CD200R1/CRTR2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain ...
TMPJ-00306	SIRP alpha Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can expre...
TMPJ-01323	NTAL Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Linker for Activation of T-Cells Family Member 2 (LAT2) is a single-pass type III membrane protein. LAT2 is highly expressed in the spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. LAT2 is invol...
TMPJ-01182	SIRP alpha Protein, Mouse, Recombinant (MIgG2a)	Mouse	HEK293 Cells
	SIRPα is a type I transmembrane glycoprotein.It contains two Ig-like C1-type domains and one Ig-like V-type domain. Mouse SIRP alpha ECD shares 61%, 75%, 62%, 61%, and 59% aa sequence identity with human, rat, equine, bo...
TMPJ-01361	Siglec-8 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8, is an approximately 75 kDa transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory mo...
TMPY-02242	Serpin B6 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	SerpinB6, also known as Cytoplasmic antiproteinase, Peptidase inhibitor 6, Placental thrombin inhibitor, SERPINB6 and PI-6, is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. SerpinB6 / PI-...
TMPH-01640	MRGPRX2 Protein, Human, Recombinant (His)	Human	E. coli
	Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Recognizes and binds small molecules ...
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SCF Protein, Human, Recombinant

TMPJ-01470

Species: Human

Expression System: E. coli

SCF Protein, Mouse, Recombinant

TMPJ-00166

Species: Mouse

Expression System: E. coli

IL-3 Protein, Mouse, Recombinant (His)

TMPJ-00051

Species: Mouse

Expression System: HEK293 Cells

Chymase 1 Protein, Mouse, Recombinant (His)

TMPH-02581

Species: Mouse

Expression System: E. coli

MCEMP1 Protein, Human, Recombinant (mFc)

TMPY-04139

Species: Human

Expression System: HEK293 Cells

Allergin-1 Protein, Mouse, Recombinant (His & Myc)

TMPH-02499

Species: Mouse

Expression System: E. coli

Chymase 1 Protein, Human, Recombinant (His)

TMPY-02574

Species: Human

Expression System: Baculovirus Insect Cells

Allergin 1 Protein, Mouse, Recombinant (hFc)

TMPY-04969

Species: Mouse

Expression System: HEK293 Cells

Chymase Protein, Canine, Recombinant (His & SUMO)

TMPH-00486

Species: Canine

Expression System: E. coli

SCF Protein, Rat, Recombinant (His)

TMPJ-00894

Species: Rat

Expression System: E. coli

CPA3 Protein, Human, Recombinant (His)

TMPH-01641

Species: Human

Expression System: E. coli

Allergin 1 Protein, Human, Recombinant (His)

TMPY-04963

Species: Human

Expression System: HEK293 Cells

Allergin 1 Protein, Human, Recombinant (hFc)

TMPY-05061

Species: Human

Expression System: HEK293 Cells

Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His)

TMPY-01027

Species: Mouse

Expression System: HEK293 Cells

TPSB2 Protein, Mouse, Recombinant (His)

TMPJ-00897

Species: Mouse

Expression System: HEK293 Cells

SCF Protein, Rat, Recombinant (HEK293, His)

TMPJ-00895

Species: Rat

Expression System: HEK293 Cells

CD117 Protein, Human, Recombinant (hFc)

TMPJ-00402

Species: Human

Expression System: HEK293 Cells

TPSAB1 Protein, Human, Recombinant (His)

TMPJ-01204

Species: Human

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)

TMPJ-01465

Species: Human

Expression System: E. coli

TSLP Protein, Human, Recombinant

TMPJ-00042

Species: Human

Expression System: E. coli

Secretogranin II Protein, Human, Recombinant (His)

TMPY-03968

Species: Human

Expression System: HEK293 Cells

CD300A Protein, Human, Recombinant (hFc & His)

TMPJ-00187

Species: Human

Expression System: HEK293 Cells

TPSB2 Protein, Human, Recombinant (E. coli, His)

TMPH-02258

Species: Human

Expression System: E. coli

TPSB2 Protein, Human, Recombinant (His & Myc)

TMPH-02257

Species: Human

Expression System: P. pastoris (Yeast)

TPSAB1 Protein, Rat, Recombinant (His & Myc & SUMO)

TMPH-03396

Species: Rat

Expression System: E. coli

TPSAB1 Protein, Mouse, Recombinant (His)

TMPH-02957

Species: Mouse

Expression System: E. coli

MRJP1 Protein, Apis mellifera, Recombinant (His)

TMPH-00064

Species: Apis mellifera

Expression System: P. pastoris (Yeast)

CD300f/CD300LF Protein, Rat, Recombinant (His & Myc & SUMO)

TMPH-03267

Species: Rat

Expression System: E. coli

TPSAB1 protein, Cynomolgus, Recombinant (His)

TMPK-01303

Species: Cynomolgus

Expression System: E. coli

MCEMP1 Protein, Mouse, Recombinant (hFc)

TMPK-01165

Species: Mouse

Expression System: HEK293 Cells

CADM1 Protein, Mouse, Recombinant (hFc)

TMPJ-00281

Species: Mouse

Expression System: HEK293 Cells

TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi)

TMPK-00038

Species: Human

Expression System: HEK293 Cells

TSLP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated

TMPK-00482

Species: Cynomolgus

Expression System: HEK293 Cells

TSLP Protein, Human, Recombinant (His & Avi)

TMPK-00037

Species: Human

Expression System: HEK293 Cells

TSLP Protein, Human, Recombinant (R127A & R130A, His & Avi), Biotinylated

TMPK-00040

Species: Human

Expression System: HEK293 Cells

TSLP Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00039

Species: Human

Expression System: HEK293 Cells

CD72 Protein, Human, Recombinant (Trx & His)

TMPJ-00898

Species: Human

Expression System: E. coli

TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (His)

TMPJ-00189

Species: Cynomolgus

Expression System: HEK293 Cells

IL-13 Protein, Human, Recombinant (His & Avi)

TMPK-00617

Species: Human

Expression System: HEK293 Cells

TSLP Protein, Mouse, Recombinant (hFc)

TMPJ-01338

Species: Mouse

Expression System: HEK293 Cells

SLP-76 Protein, Human, Recombinant (His)

TMPJ-01096

Species: Human

Expression System: E. coli

SIRP alpha Protein, Cynomolgus, Recombinant (aa 31-369, His)

TMPJ-00305

Species: Cynomolgus

Expression System: HEK293 Cells

Serpin B6 Protein, Human, Recombinant (E. coli, His)

TMPJ-00243

Species: Human

Expression System: E. coli

CD200R1/CRTR2 Protein, Human, Recombinant (His)

TMPJ-00233

Species: Human

Expression System: HEK293 Cells

SIRP alpha Protein, Human, Recombinant (His & Avi), Biotinylated

TMPJ-00306

Species: Human

Expression System: HEK293 Cells

NTAL Protein, Human, Recombinant (His)

TMPJ-01323

Species: Human

Expression System: HEK293 Cells

SIRP alpha Protein, Mouse, Recombinant (MIgG2a)

TMPJ-01182

Species: Mouse

Expression System: HEK293 Cells

Siglec-8 Protein, Human, Recombinant (mFc)

TMPJ-01361

Species: Human

Expression System: HEK293 Cells

Serpin B6 Protein, Human, Recombinant (His)

TMPY-02242

Species: Human

Expression System: Baculovirus Insect Cells

MRGPRX2 Protein, Human, Recombinant (His)

TMPH-01640

Species: Human

Expression System: E. coli

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カタログ番号	製品名
L3300	Histamine & Melatonin Receptor-Targeted Compound Library		153 compounds
	A unique collection of 153 compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS) for new drugs;

ライブラリー

Histamine & Melatonin Receptor-Targeted Compound Library

L3300

Compounds: 153